complement fixation

complement fixation
noun Date: 1906 the process of binding serum complement to the product formed by the union of an antibody and the antigen for which it is specific that occurs when complement is added to a suitable mixture of such an antibody and antigen and that is the basis of some tests to detect the presence of specific antibodies or antigens

New Collegiate Dictionary. 2001.

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  • complement fixation — n the process of binding serum complement to the product formed by the union of an antibody and the antigen for which it is specific that occurs when complement is added to a mixture (in proper proportion) of such an antibody and antigen * * *… …   Medical dictionary

  • complement fixation — n. Immunology the fixing of complement into the product of an antigen antibody reaction: used as an infection indicator in certain serologic tests that measure the presence or absence of free, active complement …   English World dictionary

  • complement fixation — noun an immune response in which an antigen antibody combination inactivates a complement (so it is unavailable to participate in a second antigen antibody combination) • Hypernyms: ↑immune response, ↑immune reaction, ↑immunologic response * * *… …   Useful english dictionary

  • complement fixation — the binding of complement to the complex that is formed when an antibody reacts with a specific antigen. Because complement is taken up from the serum only when such a reaction has occurred, testing for the presence of complement after mixing a… …   The new mediacal dictionary

  • Complement fixation test — Diagnostics MeSH D003168 The complement fixation test is an immunological medical test that can be used to detect the presence of either specific antibody or specific ant …   Wikipedia

  • complement-fixation test — n a diagnostic test for the presence of a particular antibody in the serum of a patient that involves inactivation of the complement in the serum, addition of measured amounts of the antigen for which the antibody is specific and of foreign… …   Medical dictionary

  • complement fixation — Binding of complement as a result of its interaction with immune complexes (the classical pathway) or particular surfaces (alternative pathway) …   Dictionary of molecular biology

  • complement fixation — Immunol. the binding of complement to immune complexes or to certain foreign surfaces, as those of invading microorganisms. [1905 10] * * * …   Universalium

  • complement fixation — com′plement fixa tion n. imu the binding of complement to immune complexes or to certain foreign surfaces, as those of invading microorganisms • Etymology: 1905–10 …   From formal English to slang

  • complement-fixation test — noun : a test for the presence of a particular antibody made by addition of complement and an indicator system to a mixture of known antigen and a serum suspected to contain the specific antibody for this antigen and used especially in the… …   Useful english dictionary

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